The effect of APOE ε4 allele on brain perfusion SPECT in late onset Alzheimer’s disease by an automated program, 3DSRT
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چکیده
Aim: The Apolipoprotein E (APOE) ε4 allele is a risk factor for developing Alzheimer’s disease (AD), however its impact on cerebral functional changes in AD remains controversial. Previous studies reported conflicting results or failed to confirm any association, possibly because they failed to consider either the effect of patient age at onset or that of clinical stage. We performed functional neuroimaging studies using current improved techniques to re-examine the effect of APOE ε4 allele, taking both the age at onset and clinical stage
منابع مشابه
APOE4 allele in north Indian elderly patients with dementia or late onset depression-a multiple-disease case control study
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تاریخ انتشار 2016